Publications

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2020

Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines

Nencetti, Susanna; Cuffaro, Doretta; Nuti, Elisa; Ciccone, Lidia; Rossello, Armando; Fabbi, Marina; Ballante, Flavio; Ortore, Gabriella; Carbotti, Grazia; Campelli, Francesco; Banti, Irene; Gangemi, Rosaria; Marshall, Garland R.; Orlandini, Elisabetta

Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines Journal Article

In: Journal of Enzyme Inhibition and Medicinal Chemistry, 36 (1), pp. 34–47, 2020.

Abstract | Links | BibTeX | Tags: Biochemistry, HDAC, Molecular Docking, Molecular Modeling

2016

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors

Reddy, D. Rajasekhar; Ballante, Flavio; Zhou, Nancy J.; Marshall, Garland R.

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors Journal Article

In: European Journal of Medicinal Chemistry, 127 , pp. Pages 531–553, 2016.

Abstract | Links | BibTeX | Tags: Biochemistry, HDAC, Molecular Docking

2015

Design and Synthesis of Simplified Largazole Analogs as Isoform-Selective Human Lysine Deacetylase Inhibitors

Damodara, Reddy Nandarapu; Flavio, Ballante; Timothy, Chuang; Adele, Pirolli; Biagina, Marrocco; Garland R, Marshall

Design and Synthesis of Simplified Largazole Analogs as Isoform-Selective Human Lysine Deacetylase Inhibitors Journal Article

In: Journal of Medicinal Chemistry, in press , 2015.

Abstract | Links | BibTeX | Tags: Biochemistry, HDAC, Molecular Docking, Organic Chemistry

2014

Application of Medicinal Chemistry Methods on Different Classes of Drugs

Flavio, Ballante

Application of Medicinal Chemistry Methods on Different Classes of Drugs PhD Thesis

Sapienza University of Rome, 2014.

Abstract | Links | BibTeX | Tags: 3-D QSAutogrid/R, 3D QSAR, Biochemistry, BSAO, Chemoinformatics, Chemometrics, COMBINEr, CoMFA, DABO, DockAccessor, Docking Assessment, HCV NS5B, HDAC, HIV-1, HIV-RT, HSP90, HUVEC, Ligand-Based Design, Molecular Docking, Molecular Modeling, MPGRS, NNRTIs, Opioid-Receptor Antagonists, Organic Chemistry, Pharmacophoric Model, PLS, Tuberculosis, VEGFR-2, Virtual Screening

2012

Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction

Laura, Silvestri; Flavio, Ballante; Antonello, Mai; Garland R, Marshall; Rino, Ragno

Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction Journal Article

In: Journal of Chemical Information and Modeling, 52 (8), pp. 2215-2235, 2012.

Abstract | Links | BibTeX | Tags: 3D QSAR, COMBINEr, HDAC, Molecular Docking, Molecular Modeling, PLS